abstract：:Early GF is a frequent complication following hematopoietic stem cell transplantation for patients with thalassemia. We report the outcome of double-unit CBT in three patients who developed early GF after CBT. The initial conditioning regimen consisted of i.v. Bu 14 mg/kg (day -9 to -6), i.v. Cy 200 mg/kg (day -5 to -...

journal_title：Pediatric transplantation

authors： Jaing TH,Hung IJ,Yang CP,Tsai MH,Lee WI,Sun CF

更新日期：2009-09-01 00:00:00

abstract：:IHHE as the most common vascular tumor of the liver in infancy can present with acute postnatal liver and congestive heart failure. LTx may be a lifesaving option, but can be complicated by extrahepatic involvement and bleeding complications, especially in neonates. Here we discuss the benefit of LTx in cases of acute...

journal_title：Pediatric transplantation

authors： Grabhorn E,Richter A,Fischer L,Krebs-Schmitt D,Ganschow R

更新日期：2009-08-01 00:00:00

abstract：:IMI are emerging as an important cause of mortality and morbidity among the growing number of immunocompromised children. A retrospective chart review was performed in all patients with a proven diagnosis of IMI over an eight-yr period (1997-2004) at The Hospital for Sick Children, Toronto, Canada to document the inci...

journal_title：Pediatric transplantation

authors： Al-Rezqi A,Hawkes M,Doyle J,Richardson SE,Allen U

更新日期：2009-08-01 00:00:00

abstract：:We report a 10-yr-old boy who developed CIPS after a second allogeneic BMT for severe aplastic anemia. He received the second BMT from the same HLA-matched sibling donor 16 months after the first BMT due to secondary graft failure. The preparative regimen for the second BMT consisted of fludarabine, cyclophosphamide, ...

journal_title：Pediatric transplantation

authors： Nishikawa T,Okamoto Y,Tanabe T,Shinkoda Y,Kodama Y,Tsuru Y,Kawano Y

更新日期：2009-08-01 00:00:00

abstract：:The development of NODM is a common metabolic complication after liver transplantation. Presentation of post-liver transplant diabetes mellitus with DKA is rare especially among pediatric patients. We reported three pediatric patients who presented with DKA after liver transplantation. The underlying diseases leading ...

journal_title：Pediatric transplantation

authors： Dehghani SM,Nikeghbalian S,Eshraghian A,Haghighat M,Imanieh MH,Bahador A,Kazemi K,Malek-Hosseini SA

更新日期：2009-08-01 00:00:00

abstract：:Immunosuppression regimens after liver transplantation focus mainly on preventing rejection and subsequent graft loss. However, in children, morbidity and mortality rates from infections exceed those from rejection after transplant, and immunosuppression can hinder growth, renal function, and graft tolerance. We hypot...

journal_title：Pediatric transplantation

authors： Turmelle YP,Nadler ML,Anderson CD,Doyle MB,Lowell JA,Shepherd RW

更新日期：2009-08-01 00:00:00

abstract：:Abdominal closure in children less than 10 kg following liver or kidney transplantation can be challenging. Excessive pressure attained from a tight closure can result in abdominal compartment syndrome, graft compromise and loss. Concerns over using prosthetic patches are that of infection and dehiscence. We report a ...

journal_title：Pediatric transplantation

authors： Karpelowsky JS,Thomas G,Shun A

更新日期：2009-05-01 00:00:00

abstract：:Impact of pretransplant splenectomy in patients with beta-thalassemia major undergoing an allogeneic SCT has never been addressed. Twenty-seven class III patients (29 transplants) had a pretransplant splenectomy. The outcome of these 29 transplants was compared with 76 transplants in class III who did not have a splen...

journal_title：Pediatric transplantation

authors： Mathews V,George B,Lakshmi KM,Viswabandya A,John JM,Sitaram U,Daniel D,Chandy M,Srivastava A

更新日期：2009-03-01 00:00:00

abstract：:CKD is a major co-morbidity in pediatric lung transplant recipients. We report the prevalence of renal impairment post-lung transplant at a single center, using a modified, age-adjusted eGFR for the best approximation of true GFR, and investigated associations and possible predictors of decline in renal function post-...

journal_title：Pediatric transplantation

authors： Benden C,Kansra S,Ridout DA,Shaw NL,Aurora P,Elliott MJ,Marks SD

更新日期：2009-02-01 00:00:00

abstract：:Potential age-dependent changes of sirolimus metabolite patterns in pediatric renal transplant recipients remain elusive. Thirteen pediatric solid organ transplant recipients (10 kidney, one combined liver-kidney, two liver, mean age 8.0 +/- 5.0 yr) underwent a sirolimus pharmacokinetic profile in steady-state with 10...

journal_title：Pediatric transplantation

authors： Filler G,Bendrick-Peart J,Strom T,Zhang YL,Johnson G,Christians U

更新日期：2009-02-01 00:00:00

abstract：:There are little data on prevalence of dyslipidemia in pediatric kidney TX recipients in the modern IS era. LP profiles of 38 TX recipients receiving triple IS with MMF, prednisone, and tacrolimus were compared with those of 11 children on HD using mixed model multiple linear regression analysis of repeated measures a...

journal_title：Pediatric transplantation

authors： Sgambat K,He J,McCarter RJ,Moudgil A

更新日期：2008-11-01 00:00:00

abstract：UNLABELLED:Nephrotoxicity caused by CNI may adversely affect long-term graft outcomes. For this reason, we have adopted a protocol for withdrawing TAC and converting to SRL at three months post-renal transplantation. All recipients received basiliximab induction and TAC, MMF, and prednisone. Patients without acute reje...

journal_title：Pediatric transplantation

authors： Hymes LC,Warshaw BL,Amaral SG,Greenbaum LA

更新日期：2008-11-01 00:00:00

abstract：:With the increasing adoption of steroid-sparing immunosuppression protocols in renal transplantation, it is important to evaluate any adverse effects of steroid avoidance on graft function. Early graft function, measured by CrCl was retrospectively studied in 158 consecutive pediatric renal transplant recipients from ...

journal_title：Pediatric transplantation

authors： Li L,Weintraub L,Concepcion W,Martin JP,Miller K,Salvatierra O,Sarwal MM

更新日期：2008-09-01 00:00:00

abstract：:The examination of predictors of non-adherence in transplantation populations offers the potential to identify high-risk individuals and concomitantly generate effective adherence-promoting interventions. The present paper aggregated quantitative estimates of various correlates of treatment adherence in studies of ped...

journal_title：Pediatric transplantation

authors： Kahana SY,Frazier TW,Drotar D

更新日期：2008-09-01 00:00:00

abstract：:Tailoring graft size to small paediatric recipients is a challenge. We have developed a reduced left lateral segment as an alternative to monosegment transplantation for small size recipients. Since November 2000, 89 children have been transplanted with 100 deceased donor liver grafts in our unit. Our median patient a...

journal_title：Pediatric transplantation

authors： Attia MS,Stringer MD,McClean P,Prasad KR

更新日期：2008-09-01 00:00:00

abstract：:Vascular complications post-renal transplantation are not very common and can be associated with increased risk of graft loss. We report an unusual case of a young, female teenager with asymmetrical leg swelling. After one month of transplantation, the patient developed a rise in serum creatinine with right leg swelli...

journal_title：Pediatric transplantation

authors： Vyas S,Roberti I,McCarthy C

更新日期：2008-09-01 00:00:00

abstract：:The development of malignancy in a renal transplant graft is an uncommon phenomenon. A renal neoplasm developing in the adult donor kidney of a pediatric transplant recipient has only rarely been reported. We report a case of collecting duct carcinoma arising in association with BK virus nephropathy in an adult living...

journal_title：Pediatric transplantation

authors： Emerson LL,Carney HM,Layfield LJ,Sherbotie JR

更新日期：2008-08-01 00:00:00

abstract：:Organ transplants between genetically different individuals elicit powerful immune responses that invariably cause rejection in the absence of immune suppression. Among the immune responses elicited by organ allografts, B-cell responses causing antibody-mediated rejection are one of the most vexing. However, recent ad...

journal_title：Pediatric transplantation

authors： Balin SJ,Platt JL,Cascalho M

更新日期：2008-08-01 00:00:00

abstract：:This study evaluated changes in growth parameters after pediatric heart transplantation and identified factors associated with the changes after pediatric heart transplantation (OHT). We retrospectively evaluated the somatic growth of 46 children <11 yr of age who underwent OHT for changes in weight, height, and BMI. ...

journal_title：Pediatric transplantation

authors： Peterson RE,Perens GS,Alejos JC,Wetzel GT,Chang RK

更新日期：2008-06-01 00:00:00

abstract：:MCs are important effector cells in a broad range of immune responses. Their role in liver allograft rejection is not clear. Twenty-one liver transplant recipients (mean age +/- s.d.; 10.2 +/- 4.1 yr) who experienced a rejection episode are included in this study. Biopsy specimens from normal livers (allograft biopsy ...

journal_title：Pediatric transplantation

authors： Arikan C,Nart D,Kilic M,Yuksekkaya HA,Aydogdu S

更新日期：2008-05-01 00:00:00

abstract：:Recurrent FSGS is a major challenge in the field of nephrology. To clarify the role of NPHS2 defects in the pathogenesis of FSGS recurrence, we sequenced all eight exons of NPHS2 in 11 Japanese pediatric FSGS patients with or without post-transplant recurrence. All patients had biopsy-proven primary FSGS, had no famil...

journal_title：Pediatric transplantation

authors： Furue T,Hattori M,Tsukaguchi H,Kitamura A,Oomori T,Ogino D,Nakakura H,Ashida A,Miura K,Hisano M,Takahashi K,Chikamoto H,Akioka Y,Sakano T

更新日期：2008-05-01 00:00:00

abstract：:The need for evidence-based practice guidelines requires high quality, carefully controlled clinical research trials. This multidisciplinary conference attempted to: identify urgent clinical and research issues, identify obstacles to performing clinical trials, develop concepts for organ-specific and all-organ researc...

journal_title：Pediatric transplantation

authors： Bartosh SM,Ryckman FC,Shaddy R,Michaels MG,Platt JL,Sweet SC

更新日期：2008-03-01 00:00:00

abstract：:Aspergillosis is an important cause of mortality in allogeneic HSCT. A "fungus ball" formation of Aspergillus in the bladder has seldom been reported. We report a child that underwent HSCT and developed possible disseminated aspergillosis with an intravesical "fungus ball," diagnosed by genitourinary MRI and PCR of th...

journal_title：Pediatric transplantation

authors： González-Vicent M,Lassaletta A,López-Pino MA,Romero-Tejada JC,de la Fuente-Trabado M,Díaz MA

更新日期：2008-03-01 00:00:00

abstract：:In their provocative paper, "Lung transplantation and survival in children with cystic fibrosis," Liou and colleagues state that "Prolongation of life by means of lung transplantation should not be expected in children with cystic fibrosis. A prospective, randomized trial is needed to clarify whether and when patients...

journal_title：Pediatric transplantation

authors： Sweet SC,Aurora P,Benden C,Wong JY,Goldfarb SB,Elidemir O,Woo MS,Mallory GB Jr,International Pediatric Lung Transplant Collaborative.

更新日期：2008-03-01 00:00:00

abstract：:DTI indices have been associated with cellular rejection in adult heart transplant recipients, but their predictive value in pediatric recipients is unknown. The purpose of this study was to evaluate DTI measures in the detection of cellular and AMR in pediatric heart transplant recipients. One hundred and forty-eight...

journal_title：Pediatric transplantation

authors： Behera SK,Trang J,Feeley BT,Levi DS,Alejos JC,Drant S

更新日期：2008-03-01 00:00:00

abstract：:Although the majority of pediatric solid organ transplant centers in the United States employ psychosocial criteria to assess the suitability of potential transplant candidates, there are no standardized pretransplant psychosocial assessment measures. Assessment scales that have been developed were designed for adult ...

journal_title：Pediatric transplantation

authors： Fung E,Shaw RJ

更新日期：2008-02-01 00:00:00

abstract：:CEP is a rare inborn error of porphyrin-heme synthesis. Clinical manifestations can range from mild to severe and include erythrodontia, reddish-colored urine, and hemolytic anemia that can be mild or severe and may result in splenomegaly. Completely avoiding exposure to the sun is crucial. Attempts to reduce erythrop...

journal_title：Pediatric transplantation

authors： Faraci M,Morreale G,Boeri E,Lanino E,Dallorso S,Dini G,Scuderi F,Cohen A,Cappelli B

更新日期：2008-02-01 00:00:00

abstract：:Children may have kidneys transplanted from donors larger than themselves. Abdominal wall closure may be difficult, with risks of abdominal compartment syndrome and graft compromise. Meshes used to facilitate closure may cause dense intra-abdominal adhesions, making further surgery or peritoneal dialysis difficult. We...

journal_title：Pediatric transplantation

authors： Pentlow A,Smart NJ,Richards SK,Inward CD,Morgan JD

更新日期：2008-02-01 00:00:00

abstract：:We studied tracking of BP and its impact on GFR in 44 PRTP followed for 56 months. Three months PT 77% had elevated SBP percentile. First year SBP and DBP correlated positively with final values (p < 0.0001, 0.0002, respectively). Pretransplant and three month PT SBP correlated positively (p = 0.02). At one yr, SBP an...

journal_title：Pediatric transplantation

authors： Silverstein DM,Leblanc P,Hempe JM,Ramcharan T,Boudreaux JP

更新日期：2007-12-01 00:00:00

abstract：:HPS is defined as arterial hypoxemia because of pulmonary vasodilation as a result of cirrhotic or non-cirrhotic portal hypertension. This report describes a teenager with HPS because of primary sclerosing cholangitis/autoimmune hepatitis overlap syndrome requiring OLT. HPS resolved completely within three months of O...

journal_title：Pediatric transplantation

authors： Rajwal SR,Davison SM,Prasad R,Brownlee K,McClean P

更新日期：2007-12-01 00:00:00

abstract：:To evaluate the role of BAL, CTB, and OLB in the management of pulmonary infiltrates in pediatric HSCT recipients, we conducted a retrospective review of clinical records of pediatric HSCT recipients. Data were analyzed using Chi-square for dichotomous and anova for continuous variables. Logistic regression was used t...

journal_title：Pediatric transplantation

authors： Armenian SH,Hoffman JA,Butturini AM,Kapoor N,Mascarenhas L

更新日期：2007-11-01 00:00:00

abstract：:Nonalcoholic steatohepatitis (NASH) is the most severe form of non-alcoholic fatty liver disease (NAFLD). The aim of our study was to highlight NASH as a rare but possible problem in children. We present a case of 13-yr-boy with a well-established diagnosis of liver cirrhosis secondary to NASH, who underwent orthotopi...

journal_title：Pediatric transplantation

authors： Jankowska I,Socha P,Pawlowska J,Teisseyre M,Gliwicz D,Czubkowski P,Kalicinski P,Cielecka-Kuszyk J,Socha J

更新日期：2007-11-01 00:00:00

abstract：:HBL and HCC are the most common hepatic malignancies in children. The role of OLT in children with HCC is still a matter of debate. The aim of this study was to review our experience of OLT for HCC. Medical records of patients (<18 yr) who underwent OLT for HCC were reviewed and compared to children who underwent OLT ...

journal_title：Pediatric transplantation

authors： Beaunoyer M,Vanatta JM,Ogihara M,Strichartz D,Dahl G,Berquist WE,Castillo RO,Cox KL,Esquivel CO

更新日期：2007-09-01 00:00:00

abstract：:Tacrolimus-based immunosuppression in pediatric liver transplant recipients is known to be associated with EGID. Our goal was to determine the incidence, risk factors, and characteristics of EGID in our pediatric liver transplantation program. This study was a retrospective analysis of 38 pediatric liver transplant re...

journal_title：Pediatric transplantation

authors： Lee JH,Park HY,Choe YH,Lee SK,Lee SI

更新日期：2007-08-01 00:00:00

abstract：:Combined enzyme replacement therapy (ERT) and stem cell transplant (SCT) were done for a two year old boy with severe Hurler syndrome(HS) with the aim to decrease transplant related complications. He tolerated both the procedures well without any major complications. Urine glycosaminoglycans (GAGs) decreased post-tran...

journal_title：Pediatric transplantation

authors： Soni S,Hente M,Breslin N,Hersh J,Whitley C,Cheerva A,Bertolone S

更新日期：2007-08-01 00:00:00

abstract：:An increased frequency of infections has been reported in patients with chronic liver disease. The tendency of patients in this population to acquire UTI is not completely understood. We aimed at investigating the incidence of UTI in children with cirrhosis, before liver transplantation. Twenty-six children (9 girls, ...

journal_title：Pediatric transplantation

authors： Baskin E,Ozçay F,Sakalli H,Agras PI,Karakayali H,Canan O,Haberal M

更新日期：2007-06-01 00:00:00

abstract：:LAD is a rare and fatal congenital disorder in which there is a defect of the leukocyte adhesion molecule (CD18) on neutrophils. Severe LAD results in frequent and potentially fatal infections. Although allogeneic HSCT is the only curative treatment for severe LAD, strategies for HSCT remain to be established since a ...

journal_title：Pediatric transplantation

authors： Yoshimoto A,Hashii Y,Kashiwagi H,Koizumi M,Tokimasa S,Fujisaki H,Ohta H,Hanai N,Ozono K,Hara J

更新日期：2007-06-01 00:00:00

abstract：:This single-centre, retrospective, observational pilot study was performed to evaluate the safety and efficacy of intravenous and oral itraconazole prophylaxis in paediatric haematopoietic stem cell transplantation (HCT). Study end-points were proven invasive fungal infection (IFI), survival, adverse reactions and gra...

journal_title：Pediatric transplantation

authors： Grigull L,Kuehlke O,Beilken A,Sander A,Linderkamp C,Schmid H,Seidemann K,Sykora KW,Schuster FR,Welte K

更新日期：2007-05-01 00:00:00

abstract：:Tacrolimus (Tac)-related hypertrophic cardiomyopathy (HCM) has been reported to be an unusual but serious complication affecting pediatric patients after solid organ transplantation. Herein, we present a case of young liver transplant recipient with Tac-induced HCM, treated by discontinuation of Tac followed by conver...

journal_title：Pediatric transplantation

authors： Turska-Kmieć A,Jankowska I,Pawłowska J,Kaliciński P,Kawalec W,Tomyn M,Markiewicz M,Teisseyre J,Czubkowski P,Rekawek J,Socha J

更新日期：2007-05-01 00:00:00

abstract：:Bilateral nephrectomy prior to transplantation is indicated in some patients with end-stage renal disease. The indications for bilateral nephrectomy include persistent heavy proteinuria, refractory hypertension, and urinary tract infections. We report an eight-month-old baby with male pseudohermaphroditism and renal f...

journal_title：Pediatric transplantation

authors： Martínez Urrutia MJ,Olivares Arnal P,López Pereira P,Lobato Romera R,Alonso Melgar A,Jaureguizar Monereo E

更新日期：2007-03-01 00:00:00